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Frequent diarrhea troubles your life? Experts teach you how to deal with inflammatory bowel disease

Posting time:2023-03-24 03:20:19

Frequent diarrhea troubles your life? Experts teach you how to deal with inflammatory bowel disease

If you often experience diarrhea, abdominal pain, blood in the stool, and fever in your daily life, and you don’t get better over and over again, then there may be “inflammatory bowel disease” at work. As a lifelong disease, inflammatory bowel disease cannot be cured and can only be relieved according to the guidance of a doctor. Recently, Chief Physician Zhi Min and Deputy Chief Physician Zhang Min of the Department of Gastroenterology of the Sixth Affiliated Hospital of Sun Yat-sen University visited the live broadcast room of "Dialogue with Famous Doctor Lin Xin" by the Medical Union Media, and conducted a session themed "Frequent diarrhea troubles life? Experts teach you how to deal with it." "Inflammatory Bowel Disease" live broadcast, which answered the questions related to inflammatory bowel disease that netizens were concerned about in detail.

Inflammatory bowel disease is a lifelong disease

Inflammatory bowel disease (IBD) mainly includes two diseases, one It's Crohn's disease and one is ulcerative colitis. Regarding the difference between the two, Director Zhi Min introduced. Crohn's disease mainly involves inflammation of the digestive tract from the mouth to the anus, any segment or any segment of the intestinal tract, often with ulcers, transmural inflammation or perforation. Some patients also have symptoms like anal fistula or some extraintestinal manifestations. The extraintestinal manifestations may be different for everyone, some people have extraintestinal manifestations in the skin, some people in the liver and gallbladder system, eyes, etc. Ulcerative colitis occurs primarily in the large intestine, a disease that travels up the rectum and may then involve the entire colon. It usually spreads upward from the rectum, and the lesions mainly occur in the colon. Ulcerative colitis and Crohn's disease are a little different, apart from the location of the lesions. Ulcerative colitis is mainly in the mucosa and submucosa, and the lesions are relatively shallow. The lesions of Crohn's disease are relatively deep, and the entire intestinal wall may be invaded, resulting in penetrating changes, and obstruction may gradually occur. However, both Crohn's disease and ulcerative colitis are chronic and lifelong diseases, but there is no need to panic, as long as they are controlled by medication for a long time and coexist with them, it will not affect the normal rhythm of life.

Clinical symptoms of inflammatory bowel disease

Crohn's disease and ulcerative colitis are grouped together and referred to as inflammatory bowel disease because they have similar clinical symptoms. Director Zhi Min said: "The most common clinical manifestations are diarrhea, frequent stools, blood in the stool, followed by weight loss, weight loss, and fever. Depending on the disease and severity, there may be different symptoms. For example, the lesions are in the small intestine. Patients with Crohn's disease may have more obvious abdominal pain and weight loss." Therefore, the symptoms of inflammatory bowel disease are similar, but because of the different types of diseases, the similar clinical manifestations are based on different lesion ranges and classifications. Types have different characteristics.

Inflammatory bowel disease may be related to a variety of factors

In fact, the pathogenesis of inflammatory bowel disease has not yet been understood Clearly, it may be related to genetics, environmental factors and autoimmunity. Dr. Zhang Min said, "On the basis of genetic factors and the influence of the environment, there will be problems with intestinal immunity. Excessive immunity of the intestinal tract leads to excessive inflammation, so the intestinal tract will appear congestion and edema. The clinical symptoms are abdominal pain, blood in the stool, Narrow. Environmental factors include dietary changes and changes in living environment, which may affect changes in the gut microbiome and gut flora.” That is to say, on the basis of genetics, coupled with the induction of environmental factors, lead to Abnormal immune response in the gut may be the cause of inflammatory bowel disease. However, most of the patients with inflammatory bowel disease in China are adults or adults. Children under the age of 6 are called very early-onset inflammatory bowel disease, and most of these children are genetically related, so they need to be screened. Inflammatory bowel disease may be related to genetic factors, but it is not a single-gene genetic disease. The incidence of inflammatory bowel disease in children with inflammatory bowel disease and ordinary people is similar.

Choice of Inflammatory Bowel Disease Treatment Drugs

At present, there are many main treatment drugs for inflammatory bowel disease, but how to choose is also a place that needs attention. Director Zhi Min mentioned that the current treatment drugs are actually divided into several categories. The first class of drugs are 5-aminosalicylic acid drugs, such as sulfasalazine, mesalazine, etc., which are mainly used for ulcerative colitis and very early Crohn's disease. The second category is glucocorticoid drugs, which are generally used for active Crohn's disease and ulcerative colitis, but they can only be used to control the activity of the disease, generally for about three months, and should not be used for a long time. Long-term use can have serious side effects, including osteoporosis, cataracts, and high blood pressure. Dr. Zhang Min said, "There are also drugs for immune preparations, including azathioprine, 6-mercaptopurine, methotrexate, thalidomide, cyclosporine, etc. Immune preparations can be used when Crohn's disease is active. It is superimposed with hormonal drugs, and maintained with immune preparations after hormone withdrawal. The side effects of immune preparations also include leukopenia, liver function damage and other side effects, which need to be closely monitored under the guidance of doctors, and are generally controllable." Most patients with inflammatory bowel disease All require long-term medication, but the choice of medication needs to be individualized, taking into account disease conditions, individual factors and economic factors. In addition, it is very important to conduct regular follow-up examinations according to chronic disease management, which can detect changes in the disease early and adjust the drugs for treatment in time. #family health guardian#

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